SEDOASPIS

PRODUCT INFORMATION

Sedoaspis is a product based on postbiotics activity that restores and supports the Gut–Brain Axis.

The Gut–Brain Axis is the bidirectional communication system between the gastrointestinal tract, the nervous system, and the gut microbiome. This communication occurs through neural pathways (mainly the vagus nerve), immune signaling, and the production of neurotransmitters such as serotonin, which is predominantly synthesized in the gut. When this axis is dysregulated, patients experience gastrointestinal disturbances together with emotional fluctuations, stress, sleep difficulties, and pain. Dysfunction of the gut–brain axis is involved in a range of conditions, such as: 

• Irritable Bowel Syndrome (IBS) 

• Inflammatory Bowel Diseases, such as Ulcerative Colitis 

• Parkinson’s disease, where the gut and constipation constitute an early sign of onset and inflammation 

• Conditions of reduced motility or hypersensitivity of the intestine 

• Stressful stimuli that intensify neuro‑enteric pain 

A key ingredient with a strong gut action is the postbiotic butyric acid in triglyceride form, which is the most bioavailable and stable form, ensuring that it reaches the intestine intact. Butyric acid plays a central role in gut health by improving gut motility, reducing inflammation, feeding colonocytes and strengthening the intestinal barrier. Through these mechanisms, it relieves symptoms such as constipation/diarrhea, abdominal pain and bloating. Under normal conditions, butyric acid is naturally produced during the fermentation of food in the gut by probiotics, but many patients with IBS or IBD have insufficient endogenous production — something that Sedoaspis effectively compensates for. 

In addition, Sedoaspis includes ingredients with antioxidant and anxiolytic effects. The main antioxidant component is the stigma of saffron (Crocus Sativus L), a plant with a long history of therapeutic use. Saffron’s stigmas contain highly bioactive compounds with significant antioxidant and neuro-modulating properties. According to studies, saffron helps reduce stress, regulate emotional fluctuations and improve sleep quality. Together with vitamin B6, it supports the synthesis and balance of neurotransmitters such as serotonin, contributing to a more stable mood and supporting the gut–brain axis through improved neuromodulation. 

Last but not least, Sedoaspis includes ingredients with anti-inflammatory action, as well as vitamin D3, which supports immune balance and covers the daily needs of patients with chronic inflammatory or neurodevelopmental conditions.